Article to Know on Fibrillar Absorbable Topical Hemostat and Why it is Trending?
Article to Know on Fibrillar Absorbable Topical Hemostat and Why it is Trending?
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Fibrillar Absorbable Hemostat: A Promising Aid for Bleeding Control in Colorectal Tumors
Colorectal cancer, one of the most prevalent cancers worldwide, often requires sophisticated treatment modalities to attain optimum outcomes. Among these, endoscopic submucosal dissection (ESD) has actually become a promising technique for the early-stage management of colorectal tumors. Nevertheless, the procedure's success can be tempered by postoperative problems such as delayed bleeding and perforation, as well as the obstacle of managing large mucosal defects. Additionally, exposure to gastrointestinal flora increases the risk of bacteremia and endotoxemia. In the quest for more secure and more effective options, scientists and clinicians are continually checking out alternative approaches. Fibrillar absorbable hemostat such as Surgicel ® Fibrillar ™ (Ethicon), nevertheless, emerges as a game-changer uses a multifaceted method to post-ESD care, providing both hemostatic assistance and localized bactericidal effects.
A significant product in this world is Surgi-ORC ® Fibril from Aegis Lifesciences, featuring the following key attributes:
Key Features of Surgi-ORC ® Fibril:
• Lightweight, tufted, soft and layered structure
• Provides high versatility and conformability to surgical sites
• Suitable for irregular shaped wounds and hard-to-reach areas
• Bactericidal properties
• Soft, layered product conforms and "melts in" to bleeding tissue
• Completely absorbable
• 7 layers fibrillose fabric
• Designed for hemostasis in
How does Surgi-ORC ® Fibril Work?
Surgi-ORC ® Fibrilis made up of oxidized regenerated cellulose, which, upon contact with blood, swells into a gelatinous mass, aiding in embolisms development and preventing more bleeding. Moreover, its low pH of 3.4 exhibitions powerful bactericidal properties, decreasing the risk of infection substantially.
Clinical Study Results:
A clinical study was carried out at the University of Soonchunhyang Hospital in Bucheon, Korea, clarifies the effectiveness of Surgicel ® Fibrillar ™ in colorectal ESD. In an associate of 49 patients, Surgicel ® Fibrillar ™ was successfully applied to cover the whole mucosal defect following ESD, with no Surgicel-related complications. Incredibly, none of the clients in the Surgicel group Fibrillar Absorbable Topical Hemostat experienced delayed bleeding or perforation, marking a considerable enhancement over standard ESD techniques. Furthermore, Surgicel ® Fibrillar ™ was connected with much shorter medical facility stays and lower inflammatory markers, suggesting quicker healing and enhanced postoperative results.
Fig. 1: A) Lateral spreading tumor; B) Dissected colon LST by colon endoscopic submucosal dissection.; C) Surgicel was placed onto the mucosal defect to cover the entire mucosal defect; D) Surgicel swelled into a gelatinous mass [1]
Conclusion:
In the realm of colorectal cancer treatment, every development brings us closer to our ultimate goal: enhancing client results and improving lifestyle. Fibrillar absorbable hemostat represents a critical turning point in this journey, using a powerful mix of hemostatic effectiveness and antimicrobial defense. As we continue to press the borders of development, let us accept the transformative capacity of Fibrillar absorbable hemostat and start a path towards safer, more efficient colorectal endoscopic resection.
Referrals:
[1] Myung YS, Ko BM, Han JP, Hong SJ, Jeon SR, Kim JO, Moon JH, Lee MS. Effectiveness of Surgicel® (Fibrillar) in patients with colorectal endoscopic submucosal dissection. Surgical endoscopy. 2016 Apr;30:1534-41. DOI:10.1007/s00464-015-4369-5
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